Polymeric Vehicles for Controlled Delivery

of Ayurvedic Drugs for Wound

Management

30

Arpan Biswas, Pralay Maiti, and Manoranjan Sahu

Abstract

The wound healing is a composite phenomenon as it passes through many

intricate phases, where cell-to-cell and cell-to-matrix interactions are very crucial.

Due to the complexity of wounds, different types of dressing materials are needed

for faster healing. The traditional herbal medicines have a long history for wound

management but often suffer from their low bioavailability and proper matrix

materials to hold the drug. There are various dressing materials available in the

market, but the efficient dressing materials using Ayurvedic drugs are one of the

important aspects in the present-day scenario. The wound management using

different herbal drugs loaded dressing materials will be emphasized in this

chapter. The encapsulation of herbal drug in polymer matrix increases their

efficiency toward wound healing. Polymeric dressing materials have been

discussed in details with their efficacy in terms of ex vivo, in vivo and clinical

studies. Different forms of modern dressing materials include hydrogels, patch

and scaffolds which will shed light in terms of their relative efficacy. Finally,

in vivo and clinical studies have been presented showing better wound manage-

ment using traditional herbal drugs.

Keywords

Wounds · Herbal medicines · Dressing materials

A. Biswas · P. Maiti

School of Materials Science and Technology, Indian Institute of Technology (Banaras Hindu

University), Varanasi, India

M. Sahu (*)

Department of Shalya Tantra, Institute of Medical Science, Banaras Hindu University, Varanasi,

India

e-mail: msahuvns@gmail.com

# The Author(s), under exclusive license to Springer Nature Singapore Pte

Ltd. 2022

R. C. Sobti, N. S. Dhalla (eds.), Biomedical Translational Research,

https://doi.org/10.1007/978-981-16-9232-1_30

585